Key result
A specific multi-drug anesthetic regimen is linked to lower postoperative vomiting scores versus control.
Why the study?
Does a specific anaesthetic technique including pethidine, promethazine, thiopentone, alcuronium, fentanyl, and droperidol reduce postoperative vomiting in high-risk patients compared to various other anaesthetic drugs?
Does a specific anaesthetic technique including pethidine, promethazine, thiopentone, alcuronium, fentanyl, and droperidol reduce postoperative vomiting in high-risk patients compared to various other anaesthetic drugs?
A specific anaesthetic technique including pethidine, promethazine, thiopentone, alcuronium, fentanyl, and droperidol may significantly reduce the incidence of postoperative vomiting in high-risk patients.
May reduce vomiting in high-risk patients; leaves open confirmation in randomized trials.
Twenty-eight patients who had a history of severe postoperative vomiting were divided into two groups. The first group received various anaesthetic drugs and the second group received a pethidine promethazine premedication and thiopentone, alcuronium, fentanyl and droperidol. There was a significant reduction in postoperative vomiting as assessed by vomiting score in both groups of patients, with the second group having a greater reduction in vomiting score than the control group. Nine of the patients in the second group have received the same anaesthetic uneventfully on a subsequent occasion. We propose that reassurance and the anaesthetic technique described can significantly reduce the incidence of postoperative vomiting in a high risk group.
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Fisher et al. (1984) studied History of severe postoperative vomiting (n=28). Pethidine promethazine premedication and thiopentone, alcuronium, fentanyl and droperidol vs. Various anaesthetic drugs was evaluated on Postoperative vomiting as assessed by vomiting score. A specific anaesthetic technique including pethidine, promethazine, thiopentone, alcuronium, fentanyl, and droperidol significantly reduced postoperative vomiting scores compared to control.
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