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May 1, 1989Journal of the American College of Cardiology179 citationsOpen Access

The challenge of cardiomyopathy

WAWalter H. AbelmannBLBeverly H. Lorell

Key Result

This review summarizes the clinical, pathophysiologic, and diagnostic features of principal forms of cardiomyopathy, emphasizing recent developments and unresolved questions in molecular biology.

Structured PICO

P
Population
Patients with principal forms of cardiomyopathy, including hypertrophic, dilated, restrictive, and specific cardiac muscle disease

This review summarizes the clinical features, pathogenesis, and management of major cardiomyopathies, highlighting the need for advanced molecular and genetic techniques to address unresolved questions.

Abstract

The combined clinical and pathophysiologic characteristics and diagnostic features as well as current concepts of pathogenesis, therapy and prevention of the principal forms of cardiomyopathy are reviewed. These include hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy and specific cardiac muscle disease. Emphasis is placed on recent developments and unresolved questions requiring application of newer techniques of molecular biology and genetics and adult myocyte culturing.

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Abelmann et al. (1989) conducted a review in Cardiomyopathy. This review summarizes the clinical, pathophysiologic, and diagnostic features of principal forms of cardiomyopathy, emphasizing recent developments and unresolved questions in molecular biology.

synapsesocial.com/papers/6aa6296366012019823a5931https://doi.org/10.1016/0735-1097(89)90293-3
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