Key result
Case report details recurrent Takotsubo cardiomyopathy shifting from isolated RV to LV apical ballooning.
Case Report (n=1)
No
The recurrence of Takotsubo cardiomyopathy at different cardiac locations provides evidence against the hypothesis that its variants are solely associated with anatomically fixed distributions of cardiac adrenergic receptors.
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Recurrent Takotsubo with shifting ventricular involvement may occur; challenges fixed adrenergic receptor hypothesis but remains hypothesis-generating from one case.
We report a case of Takotsubo cardiomyopathy, which involved the right ventricle at first presentation and demonstrated involvement of the left ventricle during recurrence. The patient was admitted to Kyung Hee University Hospital due to a left hip fracture, which was considered a result of physical stress. Complete recovery was confirmed by echocardiography prior to recurrence. The cause of the second event was surgery for the left hip fracture. Recurrence of Takotsubo cardiomyopathy at various cardiac locations provides evidence against the existing hypotheses that variants of Takotsubo cardiomyopathy are associated with anatomically different distributions of cardiac adrenergic receptors, the degree of stimulation by sympathetic activity and different susceptibilities to such sympathetic stimulation.
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Joe et al. (2013) conducted a case report in Takotsubo cardiomyopathy (n=1). Physical stress (hip fracture and surgery) was evaluated on Ventricular involvement during Takotsubo cardiomyopathy recurrence. An 83-year-old woman experienced recurrent Takotsubo cardiomyopathy, initially presenting with isolated right ventricular involvement and later recurring with left ventricular apical ballooning.
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