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Contact allergy to tea tree (Melaleuca alternifolia) oil has been reported several times, but there are very few publications on its sensitizing components.One proposed sensitizer in tea tree oil is ascaridole (1-3).Ascaridole (CAS 512-85-6) is a monoterpene that is derived from oxidized α-terpene.This is the first report of a study in which ascaridole was patch tested at 1% and 5% in two series of patients.
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Bakker et al. (2011) studied this question.
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