January 1, 1990Journal of the Chemical Society Chemical Communications

A novel enantiospecific synthesis of (S)-(–)-methyl 6,8-dihydroxyoctanoate, a precursor of (R)-(+)-α-lipoic acid

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Abstract

(S)-(–)-Methyl 6,8-dihydroxyoctanoate has been synthesised, with stereocontrolled reduction of methyl 8,8-dimethyl-6-oxo-octanoate using immobilised Bakers yeast as a key step.

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Dasaradhi et al. (1990) studied this question.

synapsesocial.com/papers/6aa646d8163c608a8239761e https://doi.org/10.1039/c39900000729

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Abstract

(S)-(–)-Methyl 6,8-dihydroxyoctanoate has been synthesised, with stereocontrolled reduction of methyl 8,8-dimethyl-6-oxo-octanoate using immobilised Bakers yeast as a key step.

A novel enantiospecific synthesis of (S)-(–)-methyl 6,8-dihydroxyoctanoate, a precursor of (R)-(+)-α-lipoic acid

Abstract

Discussion

Cite This Study

A novel enantiospecific synthesis of (S)-(–)-methyl 6,8-dihydroxyoctanoate, a precursor of (R)-(+)-α-lipoic acid

Abstract

Discussion

Cite This Study

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