Synthesis of Linear and Branched Perfluoroalkylated Carboxylic Acids by Radical Addition of Perfluoroalkyl Iodides to Unsaturated Fatty Acids Linear and branched perfluoroalkylated carboxylic acids, i.e. 6a, 11a, 12a, 15a and 16a, are easily available by tin(II) chloride/silver(I) acetate‐initiated free radical additions of perfluoroalkyl iodides to unsaturated carboxylic acids 1a–3a followed by tributylstannan reduction of the respective addition products. The unsaturated perfluoroalkylated carboxylic acids 7a can be obtained by regioselective base‐catalyzed elimination of HI from the addition products.
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Metzger et al. (1992) studied this question.
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