Key result
Continuous IV UFH dramatically improves massive RV thrombus in a COVID-19 patient.
Why the study?
COVID-19-related inflammation can promote a pro-thrombotic process, but right heart chambers thrombus is considered an unusual location.
Case Report (n=1)
Multimodality imaging is useful for diagnosing massive right ventricle thrombus in COVID-19 patients, which can be successfully treated with continuous intravenous unfractionated heparin.
Single-case heparin success warrants no practice change; leaves open the role of anticoagulation for COVID-19 RV thrombus.
Corona virus (COVID-19)-related inflammation can promote a pro-thrombotic process and subsequent thrombosis. Right heart chambers thrombus considered an unusual location. We report a 51-year confirmed COVID-19 infection, who presented with chest pain and severe hypoxemia. Echocardiography demonstrated a large mobile right ventricle thrombus protruding into the right ventricle outflow tract. Computed tomography angiography and cardiac magnetic resonance imaging showed the extension of the thrombus into the pulmonary trunk. Continuous intravenous unfractionated heparin infusion resulted in a dramatic clinical and echocardiographic improvement.
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Abohamr et al. (2024) conducted a case report in COVID-19 infection with massive mobile right ventricle thrombus (n=1). Continuous intravenous unfractionated heparin infusion was evaluated on Clinical and echocardiographic improvement. Continuous intravenous unfractionated heparin infusion resulted in dramatic clinical and echocardiographic improvement in a COVID-19 patient with a massive right ventricle thrombus.
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