Key result
Apical intrathoracic tumors may present as recurrent syncope without respiratory symptoms via vagus nerve involvement.
Case Report (n=2)
Recurrent syncope can be a rare initial presentation of an apical intrathoracic tumor, likely due to neurocardiogenic mechanisms involving the vagus nerve.
Alerts clinicians to consider apical tumors in unexplained recurrent syncope; leaves open confirmation in larger cohorts.
UNLABELLED: Syncope is a common complaint in clinical medical care. The etiology and mechanism can be complex. We report two cases experienced recurrent syncope to our emergency room without concomitant symptom. The image studies of both cases revealed apical neoplasms compress left common carotid artery with mediastinal lymphadenopathy and without cardiac/main artery trunk involved. After brain lesion, cardiac arrhythmia, and orthostatic hypotension were excluded, syncope related to vagus nerve involved was suspected.
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Chen Chen (2012) conducted a case report in Recurrent syncope and apical intrathoracic tumor (n=2). Apical intrathoracic tumor was evaluated on Clinical presentation and diagnosis. Apical intrathoracic tumors can initially present as recurrent syncope, potentially due to vagus nerve involvement, even in the absence of respiratory symptoms.
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