Key result
Growth hormone replacement experience in pediatric and adult patients provides mutual guidance for managing growth hormone deficiency across different age groups.
This review highlights the knowledge exchange between pediatric and adult endocrinologists regarding the management of growth hormone deficiency.
May guide integrated GHD care across ages; leaves open need for prospective trials before practice change.
Growth hormone (GH) replacement has been offered to GHdeficient (GHD) children for approximately 40 years whereas it has only been a licensed indication for the treatment of GHD adults since 1996.Nonetheless, the advent of GH replacement for adult GHD patients (Jorgensen et al ., 1989;Salomon et al ., 1989) has proved informative about the overall management of the GHD child and teenager; equally, the longstanding experience of the paediatric endocrinologist with GH replacement has provided some guidance about potential pitfalls in the diagnosis and management of the adult GHD patient.It is the knowledge exchange at this professional interface that forms the focus of this article.
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S. M. SHALET (2004) conducted a review in Growth hormone deficiency. Growth hormone replacement was evaluated. Growth hormone replacement experience in pediatric and adult patients provides mutual guidance for managing growth hormone deficiency across different age groups.
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