Key result
Carotid artery stenting before coronary artery bypass grafting in patients with severe concomitant disease was feasible and safe, with early adverse event rates of 0.5% for cardiac death and 0.5% for major ipsilateral nonfatal stroke.
Why the study?
Stroke is a serious complication of CABG, and carotid artery dysfunction is a major risk factor for stroke in patients with concomitant coronary and carotid atherosclerosis.
Does carotid artery stenting before CABG provide safe and feasible revascularization in patients with concomitant severe carotid and coronary artery disease?
Cohort (n=200)
No
Does carotid artery stenting before CABG provide safe and feasible revascularization in patients with concomitant severe carotid and coronary artery disease?
Answers are grounded in this paper and cite their sources.
Carotid artery stenting prior to CABG appears to be a feasible and safe approach for patients with concomitant severe carotid and coronary artery disease, though randomized trials are needed to compare it with open heart surgery.
Background: Atherosclerosis of the coronary and carotid arteries can be fatal.Stroke is a serious complication of coronary artery bypass graft surgery, and carotid artery dysfunction is a major risk factor for stroke (CABG).Methods: Patients who met the criteria for CABG were included in this prospective cohort study of those with severe carotid artery stenosis (>70%).Complications 30 days after stenting, neurological complications during cardiac surgery, rates of myocardial infarction (MI), and rates of death were among the outcome indicators evaluated.Results: according to outcome the mean duration of follow-up was 31.23 (±18.27SD) with range (1-60) months, according to early adverse event there were 1 (0.5%) with cardiac death, 1 (0.5%) with major Ipsilateral Nonfatal Strokes, 2 (1%) with minor strokes, there were 30 cases of cardiac death (15%), 2 cases of neurological death (1%), 4 cases of death for other reasons (2%), 2 cases of major ipsilateral nonfatal stroke (1%), 1 case of major contralateral nonfatal stroke (0.5%), 10 cases of minor ischemic stroke (5%), 12 cases of transient ischemic attack (2%), and 2 cases of nonfatal myocardial infarction (1%).Conclusion: Patients with concurrent carotid and coronary artery disease may benefit from both hybrid revascularization by CAS-CAB and phased revascularization by CAS-CAB, which are feasible, safe, and provide good short-and long-term results.Our research suggests that CAS should be considered as a feasible alternative to open heart surgery.An adequately powered randomised experiment should compare the two approaches.
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A 2023 study conducted a cohort in Concomitant coronary and carotid artery disease (n=200). Carotid artery stenting (CAS) before CABG was evaluated on Early adverse events (including cardiac death, major stroke, minor stroke, TIA, and nonfatal MI). Carotid artery stenting before coronary artery bypass grafting in patients with severe concomitant disease was feasible and safe, with early adverse event rates of 0.5% for cardiac death and 0.5% for major ipsilateral nonfatal stroke.
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