All strains of Staph. aureus isolated from pathological products are sensitive to less than 1 µg/ml of enduracidin. Strains with an heterogeneous resistance to methicillin are also sensitive to the antibiotic. Intramuscular injections of enduracidin in guinea-pigs provide the serum of the animals with a rapid and complete bactericidal action on Staph. aureus ATCC9801. A study of the activity curves shows that the speed of action of enduracidin inserum depends on the antibiotic concentration.
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Yourassowsky et al. (2009) studied this question.