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The physiologic effects of kefiran, a water-soluble exopolysaccharide, were investigated in the animal studies by oral administration of kefiran. The results in this study showed that kefiran had a hypoglycemic effect in KKAy mice and could improve defecation in the levels of fecal moisture and wet weight of feces in constipated SD rats induced by a low-fiber diet.
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Maeda et al. (2004) studied this question.
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