Benzoxaborole antimalarial agents. Part 3: design and syntheses of (carboxy‐13C‐3,3‐2H2)‐labeled and (3‐14C)‐labeled 7‐(2‐carboxyethyl)‐1,3‐dihydro‐1‐hydroxy‐2,1‐benzoxaboroles

Two new isotopically labeled compounds, (carboxy‐13C‐3,3‐2H2)‐7‐(2‐carboxyethyl)‐1,3‐dihydro‐1‐hydroxy‐2,1‐benzoxaborole (2) and (3‐14C)‐7‐(2‐carboxyethyl)‐1,3‐dihydro‐1‐hydroxy‐2,1‐benzoxaborole (3), were designed and synthesized to support the preclinical development studies of a potential new antimalarial agent, 7‐(2‐carboxyethyl)‐1,3‐dihydro‐1‐hydroxy‐2,1‐benzoxaborole (1).