Three multifunctional protein kinases, cyclic AMP-dependent protein kinase, protein kinase C, and calmodulin-dependent protein kinase II, are involved in signal transduction in response to their respective second messengers, cyclic AMP, diacylglycerol, and Ca2+. This review will summarize the key findings on calmodulin-dependent protein kinase II.
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Hitoshi Fujisawa (1990) studied this question.
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