This is the fourteenth edition of this book and celebrates its fiftieth birthday. A comparison of the first edition with the present one has shown that the original work contains 1,079 pages and the present edition 1,475. It is a tribute to the present author that he has been able to bring the work up to date with the addition of these relatively few pages. One must remember that vitamins, hormones, the types of cardiac arrhythmia and even diphtheria antitoxin, to say nothing of sulfanilamide and its derivatives, were still to be introduced into medicine in 1892. The specific infectious diseases of the first edition have been subdivided into groups according to causative agents: bacteria, viruses, rickettsias, bartonellas, fungi and protozoa. None of the "infectious diseases of doubtful nature" of the first edition are so listed in the present one. These have all been fitted into the proper places. There
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A 1943 study studied this question.