Key result
Ayurveda-based Ischemia Reversal Program linked to ~58% VO2 max increase in diabetic ischemic heart disease.
Why the study?
The study was conducted to determine the effectiveness of IRP therapy in patients with myocardial ischemia attending Madhavbaug clinics.
Does Ayurveda based non-invasive intervention (IRP therapy) improve exercise capacity and clinical parameters in patients with ischemic heart disease and diabetes?
Observational (n=121)
Yes
Does Ayurveda based non-invasive intervention (IRP therapy) improve exercise capacity and clinical parameters in patients with ischemic heart disease and diabetes?
Absolute Event Rate: 25.87% vs 16.35%
p-value: p=<0.001
A retrospective analysis suggests that a 12-week Ayurveda-based non-invasive intervention (IRP therapy) significantly improves VO2 peak and Duke Treadmill Score in patients with ischemic heart disease and diabetes.
IRP may benefit IHD patients in this cohort; hypothesis-generating, needs prospective RCTs before practice change.
Background: The aim of the study was to determine the effectiveness of IRP therapy in patients of myocardial ischemia attending Madhavbaug clinics in Vidarbha region, Maharashtra.Methods: This was a retrospective study conducted from June 2019 to December 2019, wherein we identified the data of patients suffering from IHD (positive for inducible ischemia from stress test) of either gender or any age, and who had attended the Out-patient departments (OPDs) of Madhavbaug clinics across India. The data of patients who had been administered IRP with minimum 7 sittings over a span of 12 weeks were considered for the study.Results: In the present study, medical records of 50 patients of IHD were analyzed. At the end of IRP therapy there was statistically significant reduction in weight, BMI, SBP, and DBP. VO2 peak was improved at the end of therapy i.e. 26.51±5.93 ml/kg/min as compared to baseline i.e.; 15.62±5.36 ml/kg/min and the difference was highly statistically significant (p<0.001). DTS improved from -2.93±5.88 at baseline to 3.21±6.03 at week 12 of IRP therapy and the difference was highly statistically significant (p<0.0001).Conclusions: Findings of present study suggest that IRP can serve as effective therapeutic option for the management of myocardial ischemia.
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Sane et al. (2021) conducted an observational in Ischemic heart disease and diabetes mellitus (n=121). Ischemia Reversal Program (IRP) vs. Baseline (pre-intervention) was evaluated on VO2 max (ml/kg/min) (p=<0.001). The Ayurveda-based Ischemia Reversal Program significantly improved VO2 max from 16.35 to 25.87 ml/kg/min and Duke's treadmill score over 12 weeks in patients with ischemic heart disease and diabetes.
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