Key result
Semicircular reduction annuloplasty significantly reduced early postoperative mitral regurgitation grade compared to preoperative baseline (0.57 vs 3.38; P<0.001) with no hospital or late deaths.
Why the study?
Does semicircular reduction annuloplasty combined with CABG reduce mitral regurgitation in patients with coronary artery disease and severe ischemic mitral regurgitation?
Cohort (n=21)
Does semicircular reduction annuloplasty combined with CABG reduce mitral regurgitation in patients with coronary artery disease and severe ischemic mitral regurgitation?
Absolute Event Rate: 0.57% vs 3.38%
p-value: p=<0.001
Semicircular reduction annuloplasty (Paneth-Burr technique) is an effective and safe surgical option for reducing severe ischemic mitral regurgitation in comorbid patients undergoing CABG.
Associated with reduced early MR and no mortality in ischemic MR patients undergoing CABG; leaves open need for RCTs on durability and outcomes.
BACKGROUND: Ring annuloplasty is the standard treatment of ischemic mitral regurgitation (MR), however, it has been associated with some drawbacks. It abolishes normal annular dynamics and freezes the posterior leaflet. In the present study, we evaluated Paneth suture annuloplasty in chronic ischemic MR and both early and mid-term outcomes of the technique on a selected population. METHODS: The study period was from June 2010 to June 2012. We operated on 21 patients who had the diagnosis of coronary artery disease and MR of grade 3 or 4. The patients had both a coronary artery bypass operation and the mitral semicircular reduction annuloplasty described by Paneth-Burr. The data on the patients were retrospectively collected. Patients were contacted by outpatient clinic controls for mid-term results. RESULTS: The male/female ratio was 10/11. The mean age of the patients was 71.0 ± 6.4 years. Preoperative and postoperative left ventricular ejection fraction was statistically similar (P = 0.973). Early postoperative MR grade (mean, 0.57 ± 0.51) was statistically lower than the preoperative MR grades (mean, 3.38 ± 0.50) (P < 0.001). There was no revision for excess bleeding. Two patients had prolonged hospitalization, one for sternal infection and the other for severe chronic obstructive pulmonary disease. No hospital or late postoperative deaths occurred. The mean late postoperative MR grade was 0.66 ± 0.97 degrees. One patient had progression of MR in the later follow-up, which was treated by mitral valve replacement. CONCLUSION: Semicircular reduction annuloplasty is an effective, inexpensive and easy surgical annuloplasty technique with low mortality and morbidity in severe symptomatic ischemic MR.
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Emrecan et al. (2013) conducted a cohort in chronic ischemic mitral regurgitation and coronary artery disease (n=21). Mitral semicircular reduction annuloplasty (Paneth-Burr) vs. Preoperative baseline was evaluated on Early postoperative mitral regurgitation grade (p=<0.001). Semicircular reduction annuloplasty significantly reduced early postoperative mitral regurgitation grade compared to preoperative baseline (0.57 vs 3.38; P<0.001) with no hospital or late deaths.
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