UV-vis stopped-flow results show that glutathionylcobalamin can react with nitric oxide at pH 7 to form nitrosylcob(II)alamin in a reaction second-order overall. From kinetic studies we suggest that nitric oxide attacks glutathionylcobalamin to form a caged transition state followed by formation of the nitrosylcob(II)alamin.
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Zheng et al. (2002) studied this question.
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