Key result
Persistent ST-segment elevation after primary PCI was associated with a higher rate of left ventricular aneurysm at discharge compared to no persistent ST elevation (27% vs 8%, p<0.005).
Why the study?
Does persistent ST-segment elevation after successful primary PCI correlate with adverse echocardiographic structural and functional findings in patients with first STEMI?
Population
82 consecutive patients with first ST-segment elevation myocardial infarction successfully treated by…
Comparison
Persistent ST-segment elevation at discharge vs Absence of persistent ST-segment elevation at…
Design
Cohort
Follow-up
6 months
Authors
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May flag higher-risk STEMI patients for monitoring; leaves open validation and therapeutic implications.
Cohort (n=82)
Does persistent ST-segment elevation after successful primary PCI correlate with adverse echocardiographic structural and functional findings in patients with first STEMI?
Absolute Event Rate: 27% vs 8%
p-value: p=<0.005
Persistent ST-segment elevation after successful primary PCI for STEMI is a marker for larger microvascular damage and increased risk of LV aneurysm formation, though it does not predict greater LV dilatation at 6 months.
Barchetta et al. (2007) conducted a cohort in First ST-segment elevation myocardial infarction (n=82). Persistent ST-segment elevation vs. No persistent ST-segment elevation was evaluated on Left ventricular aneurysm at discharge (p=<0.005). Persistent ST-segment elevation after primary PCI was associated with a higher rate of left ventricular aneurysm at discharge compared to no persistent ST elevation (27% vs 8%, p<0.005).
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