Key result
The TCM pattern of congealing cold and Qi stagnation was associated with restenosis after PCI (OR 4.62; 95% CI 1.37-7.86; P=0.074), while hypertension significantly increased the risk of anxiety.
Why the study?
To clarify the distribution of traditional Chinese medicine pattern types and associated risk factors after PCI, and evaluate existing reporting quality to guide standardization.
Meta-Analysis (n=10,270)
Odds Ratio: 4.62 (95% CI 1.37–7.86)
p-value: p=0.074
This meta-analysis identifies the most common traditional Chinese medicine patterns and risk factors for restenosis and anxiety in patients following percutaneous coronary intervention.
Does not support practice change; leaves open whether TCM-guided strategies reduce post-PCI restenosis.
To clarify the distribution of traditional Chinese medicine (TCM) pattern and its associated risk factors after percutaneous coronary intervention (PCI), and evaluate the reporting quality of existing studies to guide future research standardization. English databases including PubMed, Cochrane Library, and Web of Science, as well as Chinese databases including China National Knowledge Infrastructure (CNKI), China Scientific Journal Database (VIP), and Wanfang Database were searched to retrieve papers about PCI. The time span for the paper retrieval was set from the foundation of the databases to October 1, 2023. Statistical analyses were performed using Stata 12 and Python (V 3.9). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement was used to assess the reporting quality of included studies. Overall, 1 356 articles were selected, and 40 cross-sectional studies were included with 10 270 participants. The most common TCM patterns before, one to two weeks after, and six months to one year after PCI was Qi stagnation and blood stasis (n = 261, 36.45%), intertwined phlegm and blood stasis (n = 109, 27.18%), and Qi deficiency and blood stasis (n = 645, 37.03%), respectively. Smoking [odds ratio (OR) = 1.15, 95% confidence interval (CI) (0.83 – 1.47), I2= 24.7%, P = 0.257], pattern of congealing cold and Qi stagnation [OR = 4.62, 95% CI (1.37 – 7.86), I2 = 61.6%, P = 0.074], and low-density lipoprotein (LDL) [OR = 1.38, 95% CI (0.92 – 1.85), I2= 12.2%, P = 0.286] were risk factors for restenosis. Hypertension [OR = 7.26, 95% CI (3.54 – 14.88), I2= 91.6%, P = 0.001], and overweight [i.e., body mass index (BMI) > 23] [OR = 1.20, 95% CI (1.07 – 1.35), I2= 85.3%, P = 0.009] were significant risk factors of concomitant anxiety. This systematic review and meta-analysis revealed that patients with different TCM pattern types have distinct characteristics and risk factors after PCI. More high-quality studies are warranted to provide supportive evidence for future research and clinical practice.
No takes yet. Share an insight, caveat, or question.
Jieyun et al. (2024) conducted a meta-analysis in Patients undergoing percutaneous coronary intervention (PCI) (n=10,270). Traditional Chinese medicine (TCM) pattern types and clinical risk factors was evaluated on Restenosis (associated with pattern of congealing cold and Qi stagnation) (OR 4.62, 95% CI 1.37 - 7.86, p=0.074). The TCM pattern of congealing cold and Qi stagnation was associated with restenosis after PCI (OR 4.62; 95% CI 1.37-7.86; P=0.074), while hypertension significantly increased the risk of anxiety.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: