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We report 2 cases of transitional cell carcinoma, each with a single metastasis to the brain. Both patients underwent craniotomy with resection of the metastatic deposit and adjuvant whole brain radiotherapy. One patient died 4 months later of leptomeningeal carcinomatosis, while the other patient survived 1 year with no evidence of intracranial disease at autopsy despite widespread metastatic involvement of other organs.
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Bloch et al. (1987) studied this question.
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