Combination Antibiotic Therapy of Bacterial Endocarditis

Letters and Corrections1 August 1980Combination Antibiotic Therapy of Bacterial EndocarditisPHILIP C. CRAVEN, M.D., DAVID J. DRUTZ, M.D., DWIGHT M. WILLIAMS, M.D., JOHN R. GRAYBILL, M.D.PHILIP C. CRAVEN, M.D.Search for more papers by this author, DAVID J. DRUTZ, M.D.Search for more papers by this author, DWIGHT M. WILLIAMS, M.D.Search for more papers by this author, JOHN R. GRAYBILL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-2-376_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: "Combination Antibiotic Therapy of Bacterial Endocarditis" by Sande and Scheid (1) concisely and usefully summarizes several controversial areas in endocarditis treatment. We are concerned, however, that several of the recommendations poorly supported by evidence may lead to widespread use of potentially suboptimal regimens:Enterococcal Endocarditis, 4 weeks versus 6 weeks:In the absence of a comparative study, it is not clear why Mandell's carefully studied series of 38 patients supporting 6 weeks of therapy ("early, anecdotal, clinical experience and retrospective studies") should be less persuasive than the series of 13 patients and the unpublished communication cited in...References1. SANDESCHELD MW. Combination antibiotic therapy of bacterial endocarditis. Ann Intern Med. 1980;92:390-5. LinkGoogle Scholar2. DREYERFIELDS NB. Heroin-associated infective endocarditis: a report of 28 cases. Ann Intern Med. 1973;78:699-702. LinkGoogle Scholar3. NEUFIELDBRANSONMARSHALLBANKSALI GCLTN. Infective endocarditis as a complication of heroin use. South Med J. 1976;69:1148-51. CrossrefMedlineGoogle Scholar4. BANKSFLETCHERALI TRN. Infective endocarditis in heroin addicts. Am J Med. 1973;55:444-51. CrossrefMedlineGoogle Scholar5. CHERUBINBADENKAVALERLERNERCLINE CMFSW. Infective endocarditis in narcotic addicts. Ann Intern Med. 1968;69:1091-8. LinkGoogle Scholar6. CARRIZOSAKAYE JD. Antibiotic concentrations in serum, serum bactericidal activity, and results of therapy of streptococcal endocarditis in rabbits. Antimicrob Agents Chemother. 1977;12:479-83. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The University of Texas Health Science Center San Antonio, TX 78284 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCombination Antimicrobial Therapy 1 August 1980Volume 93, Issue 2Page: 376-376KeywordsAntibioticsEndocarditisRetrospective studies Issue Published: 1 August 1980 PDF DownloadLoading ...