January 1, 1983Cold Spring Harbor Symposia on Quantitative Biology

Ethidium Bromide Alters the Binding Mode of cis-Diamminedichloroplatinum(II) to pBR322 DNA

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Abstract

The molecule cis-diamminedichloroplatinum(II) (cis-DDP) is a clinically important antitumor drug (Prestayko et al. 1980), whereas the trans isomer, trans-DDP, is inactive.

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Cite This Study

Merkel et al. (1983) studied this question.

synapsesocial.com/papers/6aa6daa03f91f0dc52791dc6 https://doi.org/10.1101/sqb.1983.047.01.041

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Abstract

The molecule cis-diamminedichloroplatinum(II) (cis-DDP) is a clinically important antitumor drug (Prestayko et al. 1980), whereas the trans isomer, trans-DDP, is inactive.