Key result
Higher newborn birthweight is linked to rightward QRS axis shifts, increased amplitudes, and prolonged P/QRS durations.
Why the study?
How do electrocardiogram parameters differ systematically according to gestational age and birthweight in healthy newborns?
Cross-Sectional (n=421)
How do electrocardiogram parameters differ systematically according to gestational age and birthweight in healthy newborns?
Electrocardiogram parameters in newborns vary systematically with gestational age and birthweight, reflecting progressive right ventricular predominance and increased myocardial mass, which is important for accurately identifying cardiac hypertrophy.
Supports birthweight-adjusted ECG norms in newborns; leaves open prospective validation for hypertrophy detection.
The electrocardiograms of 421 healthy fullterm and premature newborns, recorded on the fifth day of life, were evaluated for possible systematic differences related to gestational age. All newborns were appropriate for gestational age and were divided into four groups according to birthweight. As birthweight increased, we noted: (a) a progressive rightward shifting of the QRS axis in the frontal plane; (b) an increase in the amplitude mainly of the precordial R and S waves reflecting the right ventricle and both ventricles combined, whereas a less significant increase or even a decrease was noted in the R and S waves reflecting the left ventricle; (c) a more frequent occurrence of diphasic and positive T waves in the right precordial leads; and (d) a prolongation in the duration of the P wave and the QRS complex. These findings reflect both an increase in total myocardial mass as well as a progressive right ventricular predominance, as birthweight or gestational age increases. Practical implications for electrocardiographic identification of cardiac hypertrophy in newborns of different gestational age are discussed.
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Thomaidis et al. (1988) conducted a cross-sectional in Healthy newborns (n=421). Birthweight and gestational age vs. Lower birthweight and gestational age groups was evaluated on Electrocardiogram differences (QRS axis, wave amplitudes, and durations). Increasing birthweight in healthy newborns was associated with progressive rightward shifting of the QRS axis, increased precordial R and S wave amplitudes, and prolonged P and QRS duration.
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