Key result
Elective general surgery is linked to a ~15-fold increase in CRP at 72 hours.
Why the study?
The study aimed to assess perioperative C-reactive protein as a predictor of surgical stress severity and evaluate its diagnostic accuracy for early postoperative infectious complications in elective general surgery.
Does perioperative C-reactive protein testing predict surgical stress and early postoperative infectious complications in patients undergoing elective general surgeries?
Observational (n=63)
No
Does perioperative C-reactive protein testing predict surgical stress and early postoperative infectious complications in patients undergoing elective general surgeries?
Absolute Event Rate: 42% vs 2.75%
p-value: p=0.001
The study aims to evaluate the utility of perioperative CRP testing for predicting surgical stress and early postoperative infectious complications in elective general surgery.
Marked CRP rise after elective surgery may mark stress; leaves open its value for predicting complications in this cohort.
Background and objectives Clinical diagnosis of infections, inflammatory diseases, and response monitoring can be done by C reactive protein (CRP), an acute-phase protein. CRP measurement in the perioperative period was studied, and patterns of change were analyzed, for elective general surgical patients. Study aimed to test the efficacy of C - reactive protein as a predictor for surgical stress and diagnostic accuracy to detect early postoperative infectious complications. Objective of this study was to estimate perioperative serum C - reactive protein level in patients undergoing elective surgeries. 1. To find out the relation between serum C-reactive protein level and severity of surgical stress. 2.To find out diagnostic accuracy of C-reactive protein to detect early postoperative infectious complications.
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Hussain et al. (2022) conducted an observational in Elective general surgery (n=63). Elective general surgery vs. Preoperative baseline was evaluated on Mean C-reactive protein (CRP) level at 72 hours postoperatively (p=0.001). Elective general surgery significantly increased mean CRP levels from a preoperative baseline of 2.75 mg/dl to 34.24 mg/dl at 24 hours and 42 mg/dl at 72 hours (p=0.001).
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