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Staphylococcus aureus CC398 followed fundamentally different evolutionary paths in China compared to Western countries, persisting as a human-associated MSSA lineage rather than the dominant global livestock-associated MRSA clade, and its global spread is linked to international trade in fresh pork products. Novelty: ClaimNovelty.CONTRADICTORY. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

Large-scale genomic analysis places Chinese CC398 as a persistent human-associated MSSA lineage apart from the dominant global LA-MRSA clade

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