Aorta MAO-A and SSAO activities were measured on young (3 months) and old (23-26 months) rats. A significant decrease (30-40%) in SSAO activity was found with benzylamine as substrate and the decrease was due to a reduction in Vmax. No significant changes in MAO-A activity were found in the aorta of old rats. beta-PEA is oxidized mainly by SSAO in rat aorta. However, the significance of this is unclear since the physiological role of that enzyme remains unknown.
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Danh et al. (1985) studied this question.
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