Key result
Low education linked to ~13% higher mortality in schizophrenia, a smaller increase than the general population.
Why the study?
It was unknown to what extent low educational attainment explains the increased all-cause and CVD mortality in individuals with schizophrenia compared to the general population.
Does low educational attainment increase the risk of all-cause and CVD mortality in individuals with schizophrenia to the same extent as in the general population?
Cohort (n=1,852,113)
Does low educational attainment increase the risk of all-cause and CVD mortality in individuals with schizophrenia to the same extent as in the general population?
Hazard Ratio: 1.13 (95% CI 1.05–1.21)
The association between low educational attainment and increased all-cause or CVD mortality is significantly attenuated in individuals with schizophrenia compared to the general population.
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Attenuated mortality link with low education in schizophrenia warrants caution generalizing socioeconomic risks; leaves open differential intervention targets.
Tesli et al. (2022) conducted a cohort in Schizophrenia (n=1,852,113). Low educational attainment vs. Higher educational attainment was evaluated on All-cause mortality in individuals with schizophrenia (HR 1.13, 95% CI 1.05-1.21). Low educational attainment was associated with a smaller increase in all-cause mortality risk among individuals with schizophrenia (HR 1.13; 95% CI 1.05-1.21) compared to the general population.
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