Key result
Distinct myogenic precursor myonuclei may explain the limited capacity to alter myosin heavy chain expression.
Population
Muscle fibers and myogenic precursors
Design
Review
Authors
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Caution against assuming high MHC plasticity with training; leaves open myogenic precursor contributions to fiber adaptation.
Provides a theoretical framework for understanding the limited plasticity of myosin heavy chain expression in muscle fibers through myoblast diversity.
David Parry (2001) conducted a review in Muscle fiber plasticity. A hypothetical scheme suggests that the contribution of myonuclei from distinct populations of myogenic precursors may account for the limited capacity of muscle fibers to alter myosin heavy chain expression.
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