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January 1, 1996Cancer Investigation

New Drugs: Antisense Oligodeoxynucleotides as Clinical Therapeutic Agents

John L. Tonkinson Christian Stein

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Abstract

(1996). New Drugs: Antisense Oligodeoxynucleotides as Clinical Therapeutic Agents. Cancer Investigation: Vol. 14, No. 1, pp. 54-65.

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Tonkinson et al. (1996) studied this question.

synapsesocial.com/papers/6aa71852f4c17b7aea2ee486 https://doi.org/10.3109/07357909609018436

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.Original Research · 1978 · 1,794 citations
2Antisense Oligonucleotides as Therapeutic Agents—Is the Bullet Really Magical?Original Research · 1993 · 1,303 citations
3Substrate Specificity and Kinetics of Degradation of Antisense Oligonucleotides by a 3′ Exonuclease in PlasmaOriginal Research · 1991 · 296 citations
4Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4.Original Research · 1989 · 137 citations
5Antisense inhibition of ras p21 expression that is sensitive to a point mutationOriginal Research · 1991 · 104 citations

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