Cobalt(I)-Catalyzed Diels-Alder, 1,4-Hydrovinylation and 1,4-Hydrosilylation Reactions of Non-Activated Starting Materials on a Large Scale

The transformation of non-activated starting materials with a readily accessible and easy to handle catalyst system under ambient reaction conditions is of great value for the chemo- and regioselective generation of interesting building blocks in organic synthesis. Therefore, we present the large-scale application for the cobalt-catalyzed 1,4-hydrovinylation of 1,3-dienes with terminal alkenes (Scheme [1] ), the cobalt-catalyzed Diels-Alder reactions of various non-activated alkynes with 1,3-dienes and the cobalt-catalyzed 1,4-hydrosilylation of isoprene.