Novel functionalized spiro-3-oxindoles of potential use for the synthesis of natural product analogues and pharmaceutically active compounds were prepared from substituted isatins by a convenient and versatile base-catalyzed condensation and ring-closure reaction. Moreover, a side product consisting of an at present unknown bicyclic skeleton has been isolated.
No takes yet. Share an insight, caveat, or question.
Smet et al. (2004) studied this question.