Key result
Takayasu arteritis causes sudden death via severe isolated coronary ostial stenosis in a 13-year-old girl.
Case Report (n=1)
Highlights a rare case of sudden death in a pediatric patient due to Takayasu arteritis presenting with isolated severe coronary ostial stenosis.
Prompts consideration of Takayasu arteritis in unexplained pediatric sudden death; hypothesis-generating and should not change practice.
Takayasu arteritis is a large vessel vasculitis that gives rise to inflammation-induced stenosis of the major branch arteries of the aorta. A 13-year-old girl presented with loss of appetite, palpitation, shortness of breath, and occasional chest pain. Blood examination, electrocardiography, and echocardiography revealed non-specific findings. Shortly after, she experienced severe chest pain and died suddenly. A pathological autopsy revealed severe stenosis localized only at the origin of the coronary artery, which was subsequently diagnosed as Takayasu arteritis.
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Masutani et al. (2025) conducted a case report in Takayasu arteritis with severe coronary ostial stenosis (n=1). Takayasu arteritis was evaluated on Autopsy findings and cause of death. A 13-year-old girl died suddenly from severe isolated coronary ostial stenosis caused by Takayasu arteritis, which was diagnosed upon pathological autopsy.
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