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The bone-implant interface formed in a canine distal femur was examined by means of a Raman microprobe using an implant model designed to test calcium phosphate surface coatings. By using the 960 cm-1 band of calcium phosphate to characterize the interface and adjacent mineral, we obtained spatial and compositional information about the attachment of bone to the synthetic calcium phosphate coating on a titanium support. The interface between bone and the synthetic calcium phosphate is approximately 30-40 microns in width.
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Leung et al. (1995) studied this question.
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