Key result
Rat soleus twitch zone requires ~4 times more energy for stress development than the fusion zone.
Population
Soleus muscles from adult rats
Design
Preclinical
Authors
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Suggests caution extrapolating efficiency from fused to unfused contractions in skeletal muscle; leaves open relevance to human cardiac energetics.
The energy cost of force development in rat soleus muscle is significantly higher during unfused twitches compared to fused tetani.
Loiselle et al. (1982) studied this question. Stimulation at various frequencies was evaluated on Energy cost of mean stress development. The energy cost of mean stress development in the twitch zone of adult rat soleus muscles was about four times higher than that of the fusion zone.
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