Synthesis of pharmacological dyes and their application on synthetic fabrics

Seven new azo dyes were prepared by linking various amino derivatives to barbituric acid through diazo coupling reactions. The structures of the azo dyes were identified by elemental analyses and by Fourier transform infrared, proton nuclear magnetic resonance, and mass spectral data. The barbituric acid dyes exist in five different tautomeric forms, with the Fourier transform infrared and proton nuclear magnetic resonance spectra confirming the existence of these dyes in triketo tautomeric form in the solid state and in the diketo form in the liquid state. All the compounds were tested for their antibacterial, antifungal, anticancer, and antioxidant activity. The prepared dyestuffs were dyed on polyester fabrics, and subsequently their dyeing properties and their light, washing, perspiration, rubbing, and sublimation fastness were determined.