Key result
CVD patients have ~35 mmHg higher SBP, elevated DBP, BMI, and waist circumference than controls.
Case-Control (n=200)
No
Absolute Event Rate: 159.03% vs 123.79%
p-value: p=0.001
Cardiovascular disease patients in a Nigerian cohort demonstrated significantly higher blood pressure and adiposity markers compared to healthy controls, emphasizing the importance of these risk factors in cardiovascular risk evaluation.
Observational comparison of markers in CVD vs controls leaves open causal links; larger prospective studies needed.
Background: Cardiovascular disease (CVD) remains the leading cause of death globally. CVD is strongly influenced by modifiable cardiometabolic risk factors, including elevated blood pressure and excess adiposity. Aims and Objectives: This study aimed to compare selected clinical and anthropometric markers between CVD patients and apparently healthy controls. Materials and Methods: The study included 200 participants, comprising 100 CVD subjects and 100 controls attending Federal Teaching Hospital, Owerri. The variables measured were systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), and waist circumference (WC). Results were presented as mean ± standard deviation (SD) and compared between groups using an independent-samples t-test when the assumptions for parametric analysis were satisfied. Statistical significance was set at p < 0.05. Results: There was no significant difference in age between the groups (p = 0.395). However, CVD patients had significantly higher SBP (159.03 ± 11.79 mmHg versus 123.79 ± 20.36 mmHg), DBP (91.01 ± 7.50 mmHg versus 75.68 ± 3.42 mmHg), BMI (31.04 ± 2.50 kg/m2 versus 23.28 ± 1.02 kg/m2), and WC (106.03 ± 6.94 cm versus 84.81 ± 3.01 cm) than controls (p = 0.001 for each comparison). CVD patients therefore demonstrated higher blood pressure, BMI, and waist circumference than apparently healthy subjects. Conclusion: SBP, DBP, BMI, and WC were significantly higher in CVD subjects than in controls. Pearson correlation analysis showed significant positive correlations among age, SBP, DBP, BMI, and waist circumference in CVD subjects. These findings emphasise the importance of blood pressure and adiposity assessment in cardiovascular risk evaluation. Further studies using multivariable analyses are warranted to determine the independent contribution of these factors to CVD.
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Oluchi et al. (2026) conducted a case-control in Cardiovascular disease (n=200). Cardiovascular disease vs. Apparently healthy controls was evaluated on Systolic blood pressure (SBP) (p=0.001). Cardiovascular disease patients had significantly higher systolic blood pressure (159.03 vs 123.79 mmHg, p=0.001), diastolic blood pressure, BMI, and waist circumference than healthy controls.
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