Key result
Novel fenestrated TEVAR achieves complete aortic exclusion and maintains left subclavian patency at 6 months.
Why the study?
Fenestrated TEVAR is a physiologic approach for proximal descending aortic pathology, but its application remains limited by availability, cost, and technical difficulties.
Does a two-wire system and modified olive tip facilitate implantation of fenestrated TEVAR in patients with proximal descending aortic pathology?
Case Report (n=2)
No
Does a two-wire system and modified olive tip facilitate implantation of fenestrated TEVAR in patients with proximal descending aortic pathology?
A novel two-wire system with a modified olive tip for fenestrated TEVAR demonstrated technical and clinical success in two patients with proximal descending aortic pathology.
Answers are grounded in this paper and cite their sources.
May support technical feasibility in select cases; leaves open the need for prospective validation before any practice change.
INTRODUCTION: Although Fenestrated TEVAR (F-TEVAR) has been considered to be a more physiologic approach to treat proximal descending aortic pathology, its application is still limited due to availability, cost and technical difficulties. We introduce a new design of fenestrated stent graft with a new delivery system and successfully performed first in human implantation in two patients, one with an aortic aneurysm and one with an acute aortic dissection. MATERIALS AND METHODS: The design of these two wires fenestrated stent graft include creation of an additional lumen at the side of the olive tip during manufacture, from which an additional wire can be introduced for a side branch passing into the fenestration, running inside the stent graft and exit the delivery sheath through additional hub. The two wires will facilitate delivery and deployment of the stent graft. One patient with descending aortic aneurysm and another with Stanford B aortic dissection is included in this first in human study. RESULTS: The aneurysm and dissection were completely excluded immediately after the TEVAR. Six month follow up CT showed good position of the stent graft and patent LSA in both patients. In the patient with aortic dissection, expansion of the true lumen and partial thrombosis of the false lumen was seen. CONCLUSIONS: This is a report of a two wire system in 2 patients with distal aortic arch pathology demonstrating a good technical and clinical success using pre-cannulated fenestrations through a modified nose cone olive. LEVEL OF EVIDENCE: Level 4, report of two cases.
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Adiarto et al. (2019) conducted a case report in Proximal descending aortic pathology (thoracic aortic aneurysm and acute aortic dissection) (n=2). Fenestrated TEVAR with a two-wire system and modified olive tip was evaluated on Technical and clinical success (complete exclusion of pathology and patent left subclavian artery). Implantation of a novel fenestrated stent graft using a two-wire system and modified olive tip achieved complete exclusion of aortic pathology and maintained left subclavian artery patency at 6 months in two patients.
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