Prevalence, Genotype Distribution, Risk Factors and Treatment of Cervical Human Papillomavirus Infection among Women in Dharan Municipality

BackgroundIn this study we aimed to determine the overall and type-specific prevalence of cervical human papillomavirus (HPV) infection, risk factors for such infection among women in Dharan Municipality, and treatment of those with HPV infection. MethodsIt was a descriptive observational study conducted among 3857 married women aged 30-60 years in 18 wards (Ward no.1to 20 except 4 and 7) of Dharan Municipality, Province 1, Nepal in July, 2024.Sociodemographic data and information on risk factors for cervical cancer were obtained through an interview.Cervicovaginal swab was collected for HPV DNA detection (both physician assisted and self sampling).HPV DNA testing was done in Provincial(province one) Health Laboratory (PHL) at Biratnagar by Jiangsu Macro-Micro test kit using the platform of Q-Tower 3 Analytica Jena.It was a multiplex assay and the HPV types detected were HPV 16, HPV 18, and other hrHPV (HPV 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68).Triaging was done with VIA, conventional PAP smear and/or colposcopy for International Journal of Cancer Care and Delivery binaytara.org/