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September 14, 2026Journal of the American Academy of Orthopaedic Surgeons

Forecasting US Total Knee Arthroplasty Volumes to 2040: The Shift to Ambulatory Surgery Centers Has Just Begun

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Authors

PMPaul G. MastrokostasLMLeonidas E. MastrokostasDSDivya Sheth

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Overview

Retrospective database study finds total knee arthroplasties shifting predominantly to ambulatory centers in US adults, indicating outpatient procedures will dominate volume by 2040.

Key Points

  • To model national volume trends for total knee arthroplasty across inpatient and outpatient care settings and forecast procedure growth through 2040.
  • Retrospective analysis of procedural data from the National Inpatient Sample and Nationwide Ambulatory Surgery Sample from 2016 to 2022.
  • Stratified procedures into inpatient overnight stay (length of stay ≥1 day), inpatient same-day discharge, and ambulatory surgical center (ASC) outpatient settings.
  • Modeled trends using survey-weighted regression and projected volumes through 2040 using negative binomial and autoregressive integrated moving average (ARIMA) modeling, while evaluating regional costs and payer shifts.
  • Between 2016 and 2022, inpatient TKA with stays ≥1 day declined by 85.0% and same-day inpatient discharge dropped by 46.7%, while ASC TKA procedures increased by 413.6% from 104,971 to 539,175 cases.
  • Forecasting models project annual ASC TKA volume will exceed 2.1 million procedures by 2040, led regionally by the South at an estimated 881,000 annual cases.
  • Medicare's proportion of ASC TKA cases rose from 42.5% in 2016 to 59.2% in 2022, with 2022 ASC charges ranging from $50,200 in the Midwest to $74,123 in the West.

Cite This Study

Mastrokostas et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b2e10926e14a848b17ebhttps://doi.org/10.5435/jaaos-d-26-00047
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