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September 14, 2026European Heart Journal - Quality of Care and Clinical Outcomes

Strengthening the Pre-Hospital Chain of Survival for Out-of-Hospital Cardiac Arrest

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Authors

ACAlexander CalderoneESEli SegalEBEmilie P. Belley‐Côté

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Overview

Clinical review highlights strategies to optimize pre-hospital survival chains in cardiac arrest, indicating opportunities to enhance community resuscitation outcomes.

Key Points

  • To review and synthesize interventions and system-level strategies aimed at strengthening the pre-hospital chain of survival for out-of-hospital cardiac arrest.
  • Synthesized evidence surrounding pre-hospital emergency medical service responses and community-based resuscitation interventions.
  • Evaluated key links in the resuscitation chain, including early recognition, bystander CPR, automated external defibrillator access, and advanced life support dispatch.
  • Identified prompt bystander cardiopulmonary resuscitation and early defibrillation as primary drivers of neurological recovery and overall survival.
  • Emphasized that optimized emergency dispatch protocols and community integration improve response intervals and resuscitation efficiency prior to hospital arrival.

Cite This Study

Calderone et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b2f70926e14a848b195bhttps://doi.org/10.1093/ehjqcco/qcag140
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