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September 14, 2026International Journal of Plant & Soil ScienceOpen Access

Neonicotinoid Insecticides: Chemistry, Mode of Action, Uses, Environmental Fate and Ecological Consequences

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Authors

JJJaya JosephTGThomas GeorgeBRB. Rani

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Overview

Review demonstrates widespread environmental persistence and non-target toxicity of neonicotinoids across terrestrial and aquatic ecosystems, highlighting the need for balanced regulatory frameworks.

Key Points

  • Synthesize the chemistry, modes of action, environmental fate, ecological consequences, and remediation technologies associated with neonicotinoid insecticides.
  • Literature synthesis examining neonicotinoid chemical classifications, receptor-binding mechanisms, and diverse field application methods.
  • Evaluation of environmental mobility profiles, non-target toxicity studies across multiple trophic levels, and physicochemical or biological remediation strategies.
  • High water solubility and low soil sorption enable systemic crop protection but also drive extensive contamination of surrounding soils, groundwater, and surface water.
  • Environmental residues cause substantial adverse effects in non-target organisms, particularly pollinators, aquatic invertebrates, earthworms, and birds, alongside dietary exposure pathways in mammals.
  • Available remediation approaches—including microbial breakdown, phytoremediation, and physicochemical techniques—mitigate residues but face practical limitations regarding cost, efficiency, and secondary environmental impacts.

Cite This Study

Joseph et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b2f70926e14a848b19d2https://doi.org/10.9734/ijpss/2026/v38i96320
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Status and perspective of neonicotinoid insecticides from ecological toxicity and residue2026
  2. 2Microbial-assisted remediation approach for neonicotinoids from polluted environment2024 · 8 citations
  3. 3NEONICOTINOID INSECTICIDE TOXICOLOGY: Mechanisms of Selective Action2004 · 1,734 citations
  4. 4Elucidating Neonicotinoid Exposure Risks: A Structure-Informed Review of Trends, Hazards, and a Sustainable Development Framework2026 · 1 citations
  5. 5Application, ecotoxicology and regulation of insecticides with special reference to neonicotinoids2026