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September 14, 2026PhotoniXOpen Access

Bio-integrated flexible photonics: empowering sensing, therapeutics, and interfacing

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Authors

JGJingjing GuoXGXiaoyan GuoZWZhe Wang

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Overview

Review demonstrates advances in soft optical devices across dynamic biological tissues, highlighting new capabilities for bio-integrated sensing and targeted therapeutics.

Key Points

  • To provide a comprehensive overview of recent developments in bio-integrated flexible photonics, detailing materials, structural designs, fabrication strategies, and biomedical applications.
  • Surveyed material systems that impart softness, stretchability, and biocompatibility to photonic devices.
  • Evaluated structural designs and fabrication strategies that preserve optical fidelity under mechanical deformation.
  • Categorized emerging biomedical implementations across physiological sensing, phototherapy, and tissue interfacing.
  • Flexible photonic architectures effectively overcome the mechanical mismatch between conventional rigid optical components and soft, curvilinear tissues.
  • Engineered biocompatible substrates and stretchable geometries sustain high optical performance without eliciting adverse foreign-body responses.
  • Bio-integrated photonic platforms successfully demonstrate multimodal functionalities, including dynamic biosensing, targeted light-driven therapeutics, and stable biological interfacing.

Cite This Study

Guo et al. (2026) studied this question.

synapsesocial.com/papers/6aa7b41e0926e14a848b3a79https://doi.org/10.1186/s43074-026-00285-9
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