Observational (n=39)
A newly developed radioimmunoassay for factor VII antigen reveals discrepancies between factor VII antigen levels and coagulant activity in warfarin-treated patients and those with congenital deficiency.
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Discrepancies between factor VII antigen and activity in warfarin patients and deficiency may require dual testing; leaves open assay standardization for clinical use.
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Mikami et al. (1986) conducted an observational in Congenital factor VII deficiency and warfarin therapy (n=39). Radioimmunoassay (RIA) for factor VII vs. Factor VII coagulant activity (VII:C) was evaluated on Correlation between factor VII antigen (VII:Ag) and factor VII coagulant activity (VII:C) in normal plasma (r = 0.89).
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