Left and right in the embryo is automatically defined by the formation of the anteroposterior and dorsoventral axes.In an asymmetrical organism, specification of the left-right axis must incorporate two distinct processes, the generation of asymmetry and its orientation or handedness.The orientation of the heart and abdominal organs in vertebrates is non-random and highly conserved both across and within
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Splitt et al. (1996) studied this question.
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