Key result
IV insulin reduces severe hypertriglyceridemia by ~97% in a patient with uncontrolled T2D.
Why the study?
Severe hypertriglyceridemia is extremely rare in patients with diabetes mellitus on fibrates without other risk factors and can lead to acute pancreatitis.
Does intravenous insulin infusion improve severe hypertriglyceridemia in a patient with uncontrolled type 2 diabetes on fibrates?
Case Report (n=1)
Does intravenous insulin infusion improve severe hypertriglyceridemia in a patient with uncontrolled type 2 diabetes on fibrates?
Intravenous insulin infusion can successfully manage severe hypertriglyceridemia in patients with uncontrolled type 2 diabetes.
Alerts to rare fibrate-associated severe hypertriglyceridemia in uncontrolled diabetes; leaves open risk factors and management strategies.
Hypertriglyceridemia is one of the common lipid abnormalities in patients with type2 diabetes mellitus. It is extremely rare to develop severe hypertriglyceridemia in patients with diabetes mellitus on fibrates without any other risk factors for hypertriglyceridemia. Acute pancreatitis is the main consequence of severe hypertriglyceridemia. We report a case of severe hypertriglyceridemia in a patient with uncontrolled type 2 diabetes, on fibrate and was successfully treated with intravenous insulin infusion.
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Nisahan et al. (2019) conducted a case report in Severe hypertriglyceridemia secondary to uncontrolled type 2 diabetes mellitus (n=1). Intravenous insulin infusion was evaluated on Serum triglyceride level. Intravenous insulin infusion successfully reduced severe hypertriglyceridemia from 117.4 mmol/L to 3.4 mmol/L at one month in a patient with uncontrolled type 2 diabetes.
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