Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 12, 2019Scientific ReportsOpen Access

The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids

View Full Paper
Ask AI
Bookmark
Share

Authors

SPSebastian PrillAstraZeneca (South Korea)ACAndrea CaddeoUniversity of CagliariGBGuido BaselliScience for Life Laboratory

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Prill et al. (2019) studied this question.

synapsesocial.com/papers/6aa7e08dab981def908da757https://doi.org/10.1038/s41598-019-47737-w
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rationale for using apolipoprotein B and apolipoprotein A-I as indicators of cardiac risk and as targets for lipid-lowering therapy2004 · 87 citations
  2. 2STAR: ultrafast universal RNA-seq aligner2012 · 58,410 citations
  3. 3Long‐term follow‐up of patients with NAFLD and elevated liver enzymes†‡2006 · 2,333 citations
  4. 4Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes2015 · 11,061 citations
  5. 5The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis2017 · 36 citations