Key result
Māori and Pacific ethnicity is linked to ~50% higher 28-day fatality after acute ischaemic events vs Europeans.
Why the study?
Does ethnicity affect 28-day case fatality following an acute ischaemic heart disease event?
Cohort (n=26,885)
Yes
Does ethnicity affect 28-day case fatality following an acute ischaemic heart disease event?
Odds Ratio: 1.5
Absolute Event Rate: 27.6% vs 20.5%
There are major ethnic inequalities in 28-day case fatality following acute ischaemic heart disease events in New Zealand, with Māori and Pacific people having significantly higher mortality than Europeans.
Ethnic disparities in acute IHD fatality warrant clinical awareness; leaves open whether targeted interventions narrow gaps.
BACKGROUND: The aim of this study was to investigate ischaemic heart disease (IHD) case fatality in high-risk ethnic populations in New Zealand. DESIGN: This is a national data-linkage study using anonymised hospitalisation and mortality data. METHODS: Linked individual patient data were used to identify 35-84-year-olds who experienced IHD events (acute IHD hospitalisations and/or deaths) in 2009-2010. Subjects were classified as: (i) hospitalised with IHD and alive at 28 days post-event; (ii) hospitalised with IHD and died within 28 days; (iii) hospitalised with a non-IHD diagnosis and died from IHD within 28 days; or (iv) died from IHD but not hospitalised. Multinomial logistic regression was used to estimate the proportion of people in each group, as well as overall 28-day case fatality, adjusted for ethnic differences in demographic and comorbidity profiles. RESULTS: A total of 26,885 people experienced IHD events (11.3% Māori, 4.0% Pacific and 2.5% Indian); 3.3% of people died within 28 days of IHD hospitalisations, 5.1% died of IHD within 28 days of non-IHD hospitalisations and 13.0% died of IHD without any recent hospitalisation. Overall adjusted case fatality was 12.6% in Indian, 20.5% in European, 26.0% in Pacific and 27.6% in Māori people. Compared to Europeans, the adjusted odds of death were approximately 50% higher in Māori and Pacific people and 50% lower in Indians, regardless of whether they were hospitalised. CONCLUSIONS: Major ethnic inequalities in IHD case fatality occur with and without associated hospitalisations. Improvements in both primary prevention and hospital care will be required to reduce inequalities.
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Grey et al. (2016) conducted a cohort in Ischaemic heart disease (IHD) (n=26,885). Māori and Pacific ethnicity vs. European ethnicity was evaluated on 28-day case fatality (OR 1.5). Compared to Europeans, Māori and Pacific people experiencing an acute ischaemic heart disease event had approximately 50% higher adjusted odds of 28-day case fatality (27.6% and 26.0% vs 20.5%).
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