Why the study?
Perinatal evidence on inherited cardiac channelopathies remains fragmented across disciplines, with limited synthesis of maternal, fetal, and neonatal arrhythmic vulnerability across the perinatal continuum.
Population
Forty-one studies on long QT syndrome, CPVT, Brugada syndrome, and related inherited arrhythmia syndromes across the perinatal continuum
Design
PRISMA-guided systematic review and evidence map
Key result
A systematic review of 41 studies found that arrhythmic risk in inherited channelopathies is dynamic, with heightened vulnerability during the early postpartum period.
Authors
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Supports intensified postpartum monitoring in inherited channelopathies; extends evidence on dynamic arrhythmic vulnerability.
Systematic Review (n=41)
Inherited channelopathies in pregnancy present dynamic arrhythmic risks, particularly in the early postpartum period, highlighting the need for coordinated maternal-fetal-neonatal assessment.
Andonotopo et al. (2026) conducted a systematic review in Inherited cardiac channelopathies (n=41). Pregnancy and the perinatal period was evaluated on Arrhythmic risk across the perinatal continuum. A systematic review of 41 studies found that arrhythmic risk in inherited channelopathies is dynamic, with heightened vulnerability during the early postpartum period.