Key result
Swan-Ganz placement linked to ~6-fold higher perioperative PH crisis risk in severe PAH pregnancy.
Why the study?
What are the preoperative risk factors for perioperative pulmonary hypertension crisis in pregnant women with severe PAH undergoing caesarean section?
Observational
What are the preoperative risk factors for perioperative pulmonary hypertension crisis in pregnant women with severe PAH undergoing caesarean section?
Swan-Ganz catheter placement and room air oxygenation are independent risk factors for perioperative pulmonary hypertension crisis in pregnant women with severe PAH undergoing caesarean section.
Swan-Ganz placement may elevate crisis risk in severe PAH pregnancies; leaves open whether avoidance improves outcomes.
OBJECTIVE: To analyze preoperative risk factors of perioperative pulmonary hypertension crisis (PHC) for pregnant woman with severe pulmonary artery hypertension (PAH), and approach its clinical value. METHODS: ) without oxygen, oral sildenafil ingestion, having Swan-Ganz catheter placement or not, and whether used norepinephrine or not, as well as the occurrence of perioperative PHC and clinical outcomes were collected. Possible preoperative risk factors were compared between the two groups by single factor and multiple factors logistic regression analysis. The receiver-operating characteristic curve (ROC) was plotted to assess the diagnostic value of various risk factors. RESULTS: at room air (OR = 0.882, 95%CI = 0.829-0.938, P = 0.000), Swan-Ganz catheter placement or not (OR = 6.186, 95%CI = 1.533-24.964, P = 0.010) were independent risk factors of perioperative PHC in pregnant women with severe PAH. It was shown by ROC curve analysis that the area under the ROC curve (AUC) of four factors mentioned above combined diagnosis for PHC was 0.878 (P = 0.000) with the sensitivity of 88.89% and specificity of 76.58%. CONCLUSIONS: at room air, Swan-Ganz catheter placement or not were independent risk factors of perioperative PHC for severe PAH maternal. Four preoperative factors of perioperative PHC joint diagnosis accuracy were higher.
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Zhang et al. (2017) conducted an observational in Severe pulmonary artery hypertension in pregnant women. Swan-Ganz catheter placement vs. No Swan-Ganz catheter placement was evaluated on Perioperative pulmonary hypertension crisis (PHC) (OR 6.186, 95% CI 1.533-24.964, p=0.010). Swan-Ganz catheter placement was identified as an independent risk factor for perioperative pulmonary hypertension crisis in pregnant women with severe PAH (OR 6.186; 95% CI 1.533-24.964; P=0.010).
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